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Articles

Gentle explorations of subtle physiological signals

Subtle Leptin Fluctuations

How tiny shifts in leptin maintain weight stability through delicate feedback mechanisms. Leptin, often called the satiety hormone, doesn't work as a simple on-off switch but rather as a continuous signal, one that varies subtly in response to energy status.

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Insulin Sensitivity Shifts

Understanding background adjustments in insulin sensitivity across days and weeks. Insulin sensitivity is not fixed; it changes gradually based on activity level, diet composition, circadian factors, and overall metabolic state.

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Imperceptible Ghrelin Pulses

The quiet rhythms of ghrelin, the appetite-signaling hormone, throughout the day. Rather than a continuous signal, ghrelin tends to rise and fall in pulses, creating a rhythmic pattern of appetite signaling that influences eating patterns.

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Basal Metabolic Whispers

Gentle exploration of how resting metabolic rate adjusts to changing circumstances. Your basal metabolic rate—the energy required simply to maintain basic body functions at rest—is remarkably stable but does adjust gradually over time.

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Silent NEAT Adaptations

How unconscious movement patterns quietly influence daily energy expenditure. NEAT varies widely between individuals and even within individuals across different days, yet most people remain entirely unaware of these variations.

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Faint Compensatory Responses

Subtle analysis of how the body responds to changes in energy intake or expenditure. When circumstances change, the body doesn't respond with immediate, dramatic shifts; instead, it adjusts gradually through multiple mechanisms.

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Each article explores a specific physiological mechanism in detail, with emphasis on the genuine complexity underlying weight regulation.